Le Clos du Caillou is a Châteauneuf-du-Pape estate in Courthézon, northeastern Châteauneuf-du-Pape, run by Sylvie Vacheron-Ferons. The estate farms a mix of old-vine Grenache, Syrah, Mourvèdre, and Clairette on the pebbled galets roulés soils characteristic of the northern appellation the deep river-rounded stones that store heat during the day and radiate it at night, accelerating Grenache ripening. Le Clos du Caillou produces both Châteauneuf-du-Pape Rouge and Blanc, with premium cuvées including La Reserve (Grenache/Syrah/Mourvèdre) and the Bouquet des Garrigues.

For programmes building a Châteauneuf-du-Pape section, Le Clos du Caillou provides the quality-accessible estate tier within a consistently high-performing appellation. The Courthézon terroir galets roulés, warm nights, the most northerly sector of the appellation produces wines with the weight and structure associated with Châteauneuf alongside a slightly more aromatic freshness than the more powerful southern sector productions. The estate's range covers multiple price points from the accessible entry rouge through the La Reserve prestige cuvée.